Edwin Bremer: search on Z-Library

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1

Title: A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpoint

Koopmans, Iris, Hendriks, Djoke, Samplonius, Douwe F., van Ginkel, Robert J., Heskamp, Sandra, Wierstra, Peter J., Bremer, Edwin, Helfrich, Wijnand

Journal:

Year:

2018

Language:

english

File:

PDF, 3.30 MB

english, 2018

2

Editorial: Endoplasmic Reticulum and Its Role in Tumor Immunity

Eggleton, Paul, Michalak, Marek, Bremer, Edwin

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 117 KB

english, 2015

3

MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments

Welsh, Joshua A., Van Der Pol, Edwin, Arkesteijn, Ger J.A., Bremer, Michel, Brisson, Alain, Coumans, Frank, Dignat-George, FranÃ§oise, Duggan, Erika, Ghiran, Ionita, Giebel, Bernd, GÃ¶rgens, AndrÃ©, H

Journal:

Journal of Extracellular Vesicles

Year:

2020

Language:

english

File:

PDF, 3.42 MB

english, 2020

4

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2

Edwin Bremer, Jos Kuijlen, Douwe Samplonius, Henning Walczak, Lou de Leij, Wijnand Helfrich

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

5

Therapeutic potential of Galectin-9 in human disease

Valerie R. Wiersma, Marco de Bruyn, Wijnand Helfrich, Edwin Bremer

Journal:

Medicinal Research Reviews

Year:

2012

Language:

english

File:

PDF, 714 KB

english, 2012

6

Selective elimination of pathogenic synovial fluid T-cells from Rheumatoid Arthritis and Juvenile Idiopathic Arthritis by targeted activation of Fas-apoptotic signaling

Edwin Bremer, Wayel H. Abdulahad, Marco de Bruyn, Douwe F. Samplonius, Cees G.M. Kallenberg, Wineke Armbrust, E. Brouwers, Harald Wajant, Wijnand Helfrich

Journal:

Immunology Letters

Year:

2011

Language:

english

File:

PDF, 514 KB

english, 2011

7

Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats

Yunwei Wei, Ping Chen, Marco de Bruyn, Weihui Zhang, Edwin Bremer, Wijnand Helfrich

Journal:

BMC Gastroenterology

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

8

Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cells

Edwin Bremer, Marco de Bruyn, Douwe F. Samplonius, Theo Bijma, Bram ten Cate, Lou F. M. H. de Leij, Wijnand Helfrich

Journal:

Journal of Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 389 KB

english, 2008

9

Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein

Julia Stieglmaier, Edwin Bremer, Christian Kellner, Tanja M. Liebig, Bram ten Cate, Matthias Peipp, Hendrik Schulze-Koops, Matthias Pfeiffer, Hans-Jörg Bühring, Johann Greil, Fuat Oduncu, Bertold Emme

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 626 KB

english, 2008

10

Endothelin-A-receptor antagonism with atrasentan exhibits limited activity on the KU-19-19 bladder cancer cell line in a mouse model

Edwin Herrmann, Arne Tiemann, Elke Eltze, Christian Bolenz, Christoph Bremer, Thorsten Persigehl, Lothar Hertle, Christian Wülfing

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 502 KB

english, 2009

11

GM2-ganglioside metabolism in cultured human skin fibroblasts: unambiguous diagnosis of GM2-gangliosidosis

Srinivasa Raghavan, Allan Krusell, Timothy A. Lyerla, Eric G. Bremer, Edwin H. Kolodny

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1985

Language:

english

File:

PDF, 1.04 MB

english, 1985

12

Targeted induction of apoptosis for cancer therapy: current progress and prospects

Edwin Bremer, Go van Dam, Bart Jan Kroesen, Lou de Leij, Wijnand Helfrich

Journal:

Trends in Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 527 KB

english, 2006

13

Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowthin vitroandin vivo

Marco de Bruyn, Anna A Rybczynska, Yunwei Wei, Michael Schwenkert, Georg H Fey, Rudi AJO Dierckx, Aren van Waarde, Wijnand Helfrich, Edwin Bremer

Journal:

Molecular Cancer

Year:

2010

Language:

english

File:

PDF, 875 KB

english, 2010

14

Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects

Paul Eggleton, Edwin Bremer, Joanna M Tarr, Marco de Bruyn…

Journal:

Arthritis Research & Therapy

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

15

Antibody-based fusion proteins to target death receptors in cancer

de Bruyn, Marco, Bremer, Edwin, Helfrich, Wijnand

Journal:

Year:

2013

Language:

english

File:

PDF, 523 KB

english, 2013

16

Exceptionally Potent Anti-Tumor Bystander Activity of an scFv:sTRAIL Fusion Protein with Specificity for EGP2 Toward Target Antigen-Negative Tumor Cells

Bremer, Edwin, Samplonius, Douwe, Kroesen, Bart-Jan, van Genne, Linda, de Leij, Lou, Helfrich, Wijnand

Journal:

Year:

2004

Language:

english

File:

PDF, 448 KB

english, 2004

17

Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction of cancer cell death

Brunekreeft, Kim L, Strohm, Corinna, Gooden, Marloes J, Rybczynska, Anna A, Nijman, Hans W, Grigoleit, Götz U, Helfrich, Wijnand, Bremer, Edwin, Siegmund, Daniela, Wajant, Harald, de Bruyn, Marco

Journal:

Molecular Cancer

Year:

2014

Language:

english

File:

PDF, 521 KB

english, 2014

18

CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination

Holley, Janet E., Bremer, Edwin, Kendall, Alexandra C., de Bruyn, Marco, Helfrich, Wijnand, Tarr, Joanna M., Newcombe, Jia, Gutowski, Nicholas J., Eggleton, Paul

Journal:

Multiple Sclerosis and Related Disorders

Year:

2014

Language:

english

File:

PDF, 2.94 MB

english, 2014

19

Targeted elimination of activated hepatic stellate cells by an anti-epidermal growth factor-receptor single chain fragment variable antibody-tumor necrosis factor-related apoptosis-inducing ligand (scFv425-sTRAIL)

Arabpour, Mohammad, Poelstra, Klaas, Helfrich, Wijnand, Bremer, Edwin, Haisma, Hidde J.

Journal:

The Journal of Gene Medicine

Year:

2014

Language:

english

File:

PDF, 716 KB

english, 2014

20

Direct and Indirect Rituximab-Induced T Cell Depletion: Comment on the Article by Mélet et al

Eggleton, Paul, Bremer, Edwin

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 34 KB

english, 2014

21

A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity

Wiersma, Valerie R., He, Yuan, Samplonius, Douwe F., van Ginkel, Robert J., Gerssen, Jurjen, Eggleton, Paul, Zhou, Jin, Bremer, Edwin, Helfrich, Wijnand

Journal:

British Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 190 KB

english, 2014

22

50. Adenoviral-Mediated Gene Transfer of Single Chain Fv 425:sTRAIL Fusion Protein Induces Target Cell Restricted Apoptosis in EGFR- Positive Tumor Cells and a Potent Bystander Effect

Haisma, Hidde J., Dijkstra, Marike, Bremer, Edwin, Helfrich, Wijnand

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

23

The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells

Wiersma, Valerie R, de Bruyn, Marco, van Ginkel, Robert J, Sigar, Emily, Hirashima, Mitsuomi, Niki, Toshiro, Nishi, Nozomu, Samplonius, Douwe F, Helfrich, Wijnand, Bremer, Edwin

Journal:

The Journal of Investigative Dermatology

Year:

2012

Language:

english

File:

PDF, 246 KB

english, 2012

24

Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity

Wiersma, Valerie R., Michalak, Marek, Abdullah, Trefa M., Bremer, Edwin, Eggleton, Paul

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

25

The Ever-Expanding Immunomodulatory Role of Calreticulin in Cancer Immunity

de Bruyn, Marco, Wiersma, Valerie R., Helfrich, Wijnand, Eggleton, Paul, Bremer, Edwin

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

26

Targeting of the Tumor Necrosis Factor Receptor Superfamily for Cancer Immunotherapy

Journal:

Year:

2013

Language:

english

File:

PDF, 4.92 MB

english, 2013

27

Potent Systemic Anticancer Activity of Adenovirally Expressed EGFR-Selective TRAIL Fusion Protein

Bremer, Edwin, van Dam, Gooitzen M, de Bruyn, Marco, van Riezen, Manon, Dijkstra, Marike, Kamps, Gera, Helfrich, Wijnand, Haisma, Hidde

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 721 KB

english, 2008

28

CD20 + T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer

de Bruyn, Marco, Wiersma, Valerie R, Wouters, Maartje C A, Samplonius, Douwe F, Klip, Harry G, Helfrich, Wijnand, Nijman, Hans W, Eggleton, Paul, Bremer, Edwin

Journal:

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

29

Calreticulin, a therapeutic target?

Eggleton, Paul, Bremer, Edwin, Dudek, Elzbieta, Michalak, Marek

Journal:

Expert Opinion on Therapeutic Targets

Year:

2016

Language:

english

File:

PDF, 676 KB

english, 2016

30

Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5

He, Yuan, Hendriks, Djoke, van Ginkel, Robert, Samplonius, Douwe, Bremer, Edwin, Helfrich, Wijnand

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 524 KB

english, 2016

31

Antibody-based targeting of TNF-ligands for cancer therapy

Journal:

New Horizons in Translational Medicine

Year:

2015

Language:

english

File:

PDF, 52 KB

english, 2015

32

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction

Hendriks, Djoke, He, Yuan, Koopmans, Iris, Wiersma, Valerie R., van Ginkel, Robert J., Samplonius, Douwe F., Helfrich, Wijnand, Bremer, Edwin

Journal:

Year:

2016

Language:

english

File:

PDF, 3.08 MB

english, 2016

33

A versatile pretargeting approach for tumour-selective delivery and activation of TNF superfamily members

He, Yuan, van Bommel, Peter E., Samplonius, Douwe F., Bremer, Edwin, Helfrich, Wijnand

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.01 MB

english, 2017

34

CD47, a multi-facetted target for cancer immunotherapy

Wiersma, Valerie R, van Bommel, Peter E, de Bruyn, Marco, Helfrich, Wijnand, Bremer, Edwin

Journal:

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Year:

2017

Language:

english

File:

PDF, 603 KB

english, 2017

35

The multifaceted role of autophagy in cancer and the microenvironment

Folkerts, Hendrik, Hilgendorf, Susan, Vellenga, Edo, Bremer, Edwin, Wiersma, Valerie R.

Journal:

Medicinal Research Reviews

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

36

Bispecific antibody approach for improved melanoma-selective PD-L1 immune checkpoint blockade.

Koopmans, Iris, Hendriks, Mark A.J.M., van Ginkel, Robert J., Samplonius, Douwe F., Bremer, Edwin, Helfrich, Wijnand

Journal:

The Journal of Investigative Dermatology

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

37

Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis?

Bouwstra, Renee, van Meerten, Tom, Bremer, Edwin

Journal:

Molecular & Cellular Oncology

Year:

2019

Language:

english

File:

PDF, 721 KB

english, 2019

38

Bispecific antibody approach for improved melanoma-selective PD-L1 immune checkpoint blockade.

Koopmans, Iris, Hendriks, Mark A.J.M., van Ginkel, Robert J., Samplonius, Douwe F., Bremer, Edwin, Helfrich, Wijnand

Journal:

The Journal of Investigative Dermatology

Year:

2019

File:

PDF, 1.65 MB

2019

39

Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes

Wiersma, Valerie R., Clarke, Alex, Pouwels, Simon D., Perry, Elizabeth, Abdullah, Trefa M., Kelly, Clive, Soyza, Anthony De, Hutchinson, David, Eggleton, Paul, Bremer, Edwin

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 3.08 MB

english, 2019

40

CD47 expression defines efficacy of rituximab with CHOP in Non-Germinal Center B-cell (non-GCB) Diffuse Large B-Cell Lymphoma patients (DLBCL), but not in GCB DLBCL

Bouwstra, Renee, He, Yuan, de Boer, Janneke Willemien, Kooistra, Hilde, Cendrowicz, Ewa, Fehrmann, Rudolf S.N., Ammatuna, Emanuele, Eulenburg, Christine, Nijland, Marcel, Huls, Gerwin, Bremer, Edwin,

Journal:

Cancer Immunology Research

Year:

2019

Language:

english

File:

PDF, 3.39 MB

english, 2019

41

EpCAM-targeted induction of apoptosis

Journal:

Frontiers in Bioscience

Year:

2008

Language:

english

File:

PDF, 305 KB

english, 2008

42

Low-dose metformin reprograms the tumor immune microenvironment in human esophageal cancer: Results of a phase II clinical trial

Wang, Shuhong, Lin, Yusheng, Xiong, Xiao, Wang, Lu, Guo, Yi, Chen, Yuping, Chen, Shaobin, Wang, Geng, Lin, Peng, Chen, Hongcai, Yeung, Sai-Ching J, Bremer, Edwin, Zhang, Hao

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 11.74 MB

2020

43

The Neutrophil: The Underdog That Packs a Punch in the Fight against Cancer

Ustyanovska Avtenyuk, Natasha, Visser, Nienke, Bremer, Edwin, Wiersma, Valerie R.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.39 MB

2020